Profile
Matthew Johnson
Assistant / London
Practice & Professional Experience
Matthew joined D Young & Co in 2008. His practice focuses on prosecution of patent applications and opinion work relating to the pharmaceutical, medical science and chemical industries.
Prior to entering the patent law profession, Matthew worked for 7 years as a medicinal chemist for one of the world’s largest pharmaceutical companies. He specialised in the lead optimisation of new chemical entities for treatment of neurological conditions. In the course of his work he received an Exceptional Science Award for the development of a synthetic route toward a key series of 5-azaindole CB2 agonists.
Matthew has co-authored papers in several peer-reviewed journals and has been a co-inventor on a number of patents/patent applications. He has presented his research at national and international conferences.
Qualifications
MChem in Chemistry with Pharmacology, University of Liverpool.
Certificate in Intellectual Property Law, Queen Mary College, University of London.
Memberships
Student Member of the Chartered Institute of Patent Attorneys (CIPA).
Selected Publications
Pyridazine derivatives for inhibiting beta-amyloid peptide production and their preparation, pharmaceutical compositions and use in the treatment of Alzheimer’s disease. PCT Int. Appl. WO 2009050227
Discovery of 1-[4-(3-Chlorophenylamino)-1-methyl-1H-pyrrolo[3,2-c]pyridin-7-yl]-1-morpholin-4-ylmethanone, a Brain Penetrant 5-Azaindole CB2 Agonist for the Treatment of Chronic Pain. Journal of Medicinal Chemistry, (2009), 52(19), 5785-5788.
Identification of Novel Glycine Sulphonamide Antagonists for the EP1 Receptor. Bioorg & Med. Chem. Lett., (2007), 17(6), 1750-1754
1,5-Biaryl Pyrrole Derivatives as EP1 Receptor Antagonists: Structure-activity Relationships of 6-substituted and 5,6-disubstituted Benzoic Acid Derivatives. Bioorg. Med. Chem. Lett., (2007) 17(4), 916-920.
Structure-activity Relationships of 1,5-Biaryl Pyrrols as EP1 Receptor Antagonists. Bioorg. Med. Chem. Lett., (2006), 16(4), 3657-3662.
Preparation of Pyrrolopyridine Derivatives as Cannabinoid Receptor Modulators. PCT Int. Appl. WO 2005121140 and EP1753764B.
